00:00Today, we bring you an incredible breakthrough in cancer treatment.
00:03The first UK patients are now receiving an experimental mRNA therapy for cancer.
00:08Introducing mRNA, 4359, a cutting-edge immunotherapy.
00:13This revolutionary treatment aims to train the immune system to recognize and attack
00:17cancer cells.
00:19The therapy uses messenger RNA to present common markers of tumors, helping the body's
00:23immune system identify and fight cancer more effectively.
00:27This treatment is part of a global phase half-clinical trial happening right here at
00:31Imperial College Healthcare NHS Trust.
00:33Dr. Nikola Awosika, member of the clinical research delivery team that delivered the
00:38first dose of mRNA-4359 in the UK, said,
00:43It's exciting to contribute to innovative treatments like this.
00:47We are grateful for our patients' participation.
00:50The trial is a collaboration between Imperial College London and Imperial College Healthcare
00:55NHS Trust.
00:56It aims to treat melanoma, lung cancer, and other solid tumors.
01:01Patients are receiving mRNA-4359 alone, or combined with pembrolizumab, an existing cancer
01:07drug, to test safety and effectiveness.
01:10Dr. David Panotto, a clinician scientist at Imperial College London's Department of Surgery
01:15in Cancer and consultant medical oncologist at Imperial College Healthcare NHS Trust,
01:20said,
01:21New mRNA therapies offer a new avenue for recruiting the patient's own immune system
01:26to fight cancer.
01:27We're laying crucial groundwork for future treatments.
01:30An 81-year-old man with treatment-resistant melanoma was the first to receive this therapy.
01:36He expressed relief and hope, knowing he's contributing to a potential game-changer.
01:40Nearly one in two people in the UK will face cancer.
01:44Traditional treatments sometimes fail, but this new mRNA therapy offers hope for more
01:49effective, less toxic options.
01:51Secretary of State for Health and Social Care, Victoria Atkins, said,
01:56Cancer can affect any of us, be it through devastating diagnosis, the difficulties faced
02:01during treatment, or the loss of a loved one.
02:04But huge progress is being made, and survival rates are at an all-time high.
02:08Join us in supporting this groundbreaking trial.
02:11Share this video and comment below with your thoughts.
02:14Together, we can turn the tide against cancer.
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