vcclab.org. Overview of the many logP and other physical property calculators available commercially and on-line. XLOGP3, a simple LogP estimator used by PubChem (release 2021.05.07)

LogP is an important molecular physical property that impacts a wide range of systems. Used in conjunction with other critical parameters, it can help drive research forward in many industries and …

LogP is the log of the partition coefficient of a solute between octanol and water, at near infinite dilution. LogP is widely used in drug discovery and development as an indicator of potential utility of a solute …

Jan 6, 2024 · LogP measures the logarithm of ration between the concentration of a compound in a non-polar solvent and in water. It is common practice to measure this using octanol (PubChem 2003) as …

Introduction Symbols Definition of Partition Coefficient P and Distribution Coefficient D Micro Partition Coefficient Relation Between Macro and Micro Partition Coefficients LogP calculation methods …

The logP value, representing a compound's partition coefficient between octanol and water, is a critical parameter in computer-aided drug design (CADD) and various molecular applications due to its …

Introduction Carefully planning chemical modification and labeling procedures includes determining the appropriate solvents for the specific reagents and reactants that will be used. Peptides and proteins …

A measure of the preference of a compound to dissolve in either water or an organic solvent (such as octanol) when uncharged. More technically, it is the logarithm of the partition coefficient (P) of a …

Octanol-water partition coefficient logP is used in QSAR studies and rational drug design as a measure of molecular hydrophobicity. Hydrophobicity affects drug absorption, bioavailability, hydrophobic drug …

Examples for logP and logD calculations The following examples show log P /log D results for special molecules types. The calculations were performed with the default settings of the log P plugin. …