This document translates screening guidance and clinical considerations from the USPSTF and CDC into a decision tree format to guide implementation. (e.g., every 3 to 6 months) if they …

These comprehensive recommendations are the first published by CDC on laboratory testing for syphilis, which has traditionally been based on serologic algorithms to detect a humoral …

Follow rapid plasma reagin titers. Possible syphilis (early or latent) or previously treated syphilis. Historical and clinical evaluation required. Probable false-positive syphilis IgG antibody test. …

Papp JR, Park IU, Fakile Y, et al. CDC laboratory recommendations for syphilis testing, United States, 2024. MMWR Recomm Rep. 2024;73(1):1-32. Workowski KA, Bachmann LH, Chan …

testing algorithm – the reverse sequence testing algorithm – (a misnomer) is the one in which serum is initially tested using a specific treponemal test and confirmed with a non-treponemal …

In interpreting serologies, it is helpful to know which testing algorithm (traditional vs reverse) is being used in your lab. False positive immunoassays can occur with Lyme disease or non …

Syphilis screening at CHI Health Laboratory is performed by using the reverse algorithm, which first tests sera for T pallidum specific IgG/IgM antibodies using an automated MFI. A positive …

Interpretation of Syphilis Serology Traditional Algorithm1 . 1. Screen with non -treponemal test (RPR/VDRL). 2. Confirm reactive non-treponemal test with treponemal test. *Primary syphilis …

1. C-DPH Recommended Algorithm. Algorithms used by laboratories may vary. Check with your laboratory provider. 2. When ordering an RPR=rapid plasma reagin (non-treponemal) and …

Syphilis Test Algorithm Revised 031919 J Flanagan, Ph.D. 7 Reactive Non-reactive Non-reactive Mostly likely a false-positive test result, but syphilis cannot be entirely ruled out. If clinical …