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  1. Tear metabolomics highlights new potential biomarkers for ...

    Oct 1, 2021 · The lacrimal exocrinopathy of primary Sjögren's syndrome (pSS) is one of the main causes of severe dry eye syndrome and a burden for patients. Early recognition and treatment …

  2. Tear Metabolomes Differentiate Primary Sjögren Syndrome From …

    Aug 30, 2021 · Cornea showing dry eye. The study also identified 9 key metabolites that may be useful in the development of Sjögren syndrome therapeutics. Tears contain a metabolomic …

  3. Tear metabolomics help differentiate Sjogren's syndrome from …

    Oct 17, 2023 · France: Tear metabolomics help differentiate Sjogren's syndrome from other dry eye diseases finds new study published in Ocular surface. This study discovered a …

  4. Tear Cytokine Levels in Sicca Syndrome-Related Dry Eye: A Meta

    Apr 28, 2023 · A cohort study of T helper 17 cell-related cytokine levels in tear samples of systemic lupus erythematosus and Sjögren’s syndrome patients with dry eye disease.

  5. New Discoveries in Sjögren’s Disease - The Rheumatologist

    Oct 22, 2024 · Sjögren’s disease is evolving as physicians and researchers better understand its causes and types. One recent change has been a renaming, from Sjögren’s syndrome to …

  6. The primary objective of this study was to evaluate the safety and tolerability of 22 and 44 mM Lacripep ophthalmic solution versus placebo (vehicle) administered 3 times daily for 28 days in …

  7. Identification of potential salivary biomarkers for Sjögren

    Aug 27, 2023 · Introduction Despite the rise of metabolomics over the past years, and particularly salivary metabolomics, little research on Sjögren’s syndrome (SS) biomarkers has focused on …

  8. Abstract Purpose. The lacrimal exocrinopathy of primary Sjögren’s syndrome (pSS) is one of the main causes of severe dry eye syndrome and a burden for patients. Early recognition and …

  9. Frontiers | Tear miRNAs Identified in a Murine Model of Sjögren’s ...

    Mar 4, 2022 · Thus, we propose that dysregulated tear microRNA may serve as indicators of LG disease in Sjögren’s syndrome and might also provide insights into disease pathogenesis. …

  10. Metabolomics and lipidomics approaches in human tears: A …

    Jul 1, 2022 · Chen and coworkers identified a total of 156 metabolites, among which 34 metabolites were dysregulated in DED (multivariate analysis; P < 0.05). 24 The metabolomics …