In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture. [1] Such control is also often …

In addition to problems of safety, reprogramming thus far been a very inefficient process – only about one in every 1,000 mature cells is successfully reprogrammed.

This review discusses the scientific framework that led to the reprogramming of induced pluripotent stem cells (iPSCs), the roles of the OSKM in reprogramming the mature …

3 days ago · Cell reprogramming is the process of reverting mature, specialised cells into induced pluripotent stem cells. Reprogramming also refers to the erasure and re-establishment of …

Aug 24, 2023 · Chemical reprogramming offers an unprecedented opportunity to control somatic cell fate and generate desired cell types including pluripotent stem cells for applications in …

Dec 13, 2024 · Cell reprogramming is the act of reverting mature, specialised cells into induced pluripotent stem cells, also known as iPS cells. This process requires a stem or progenitor cell …

In 2006, scientists led by Shinya Yamanaka at Kyoto University in Japan pioneered a new technology, known as induced pluripotent stem cells, or iPSC for short. This breakthrough …

Oct 6, 2023 · A strategy for cellular reprogramming involves using targeted genetic interventions to engineer a cell into a new state. The technique holds great promise in immunotherapy, for …

2 days ago · Cellular reprogramming involves changing a cell’s identity or developmental potential. This concept in biology and medicine challenges the traditional understanding that …

Mar 27, 2025 · This review summarizes the recent advances in cell reprogramming mediated by transcription factors or chemical molecules, followed by elaborating on the important roles of …