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  1. Inclisiran: Uses, Dosage, Side Effects, Warnings - Drugs.com

    Jan 22, 2025 · Inclisiran is used to lower LDL-C (low-density lipoprotein cholesterol) levels alongside diet and statin therapy in adults with high cholesterol caused by genetic reasons …

  2. Inclisiran - Wikipedia

    Inclisiran is a small interfering RNA that acts as an inhibitor of an enzyme that degrades LDL receptors and thereby increases LDL levels in the blood. Since Inclisiran inhibits degradation …

  3. Inclisiran (subcutaneous route) - Side effects & uses

    Feb 1, 2025 · Inclisiran injection is used together with a proper diet, alone or together with other medicines (eg, statins), to treat heterozygous familial hypercholesterolemia (HeFH) in patients …

  4. Inclisiran contains a covalently linked ligand containing three N acetylgalactosamine (GalNAc) residues to facilitate delivery to hepatocytes. With one exception, the 2'ribose moieties of the...

  5. FDA approves Novartis Leqvio® (inclisiran), first-in-class siRNA …

    Dec 22, 2021 · Leqvio is indicated in the United States as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with clinical atherosclerotic cardiovascular …

  6. Inclisiran: what you need to know about this cholesterol-lowering …

    Everything you need to know about inclisiran. Find out how it works, who is eligible and the common side effects.

  7. Inclisiran injection (Leqvio) - Patient

    Apr 20, 2025 · Inclisiran (Leqvio®) injections lower the level of LDL cholesterol in your blood. Inclisiran is actually a small piece of RNA which is absorbed by liver cells after being injected. …

  8. Inclisiran for hypercholesterolaemia - Australian Prescriber

    Jun 18, 2024 · Inclisiran is a small interfering ribonucleic acid injection, approved to reduce low-density lipoprotein cholesterol in adults with hypercholesterolaemia or atherosclerosis, or at …

  9. Inclisiran injection: MedlinePlus Drug Information

    Inclisiran injection is in a class of medications called proprotein convertase subtilisin kexin type 9 (PCSK9)-interfering mRNA. It works by decreasing the amount of LDL cholesterol in the blood …

  10. DailyMed - LEQVIO- inclisiran injection, solution

    Jun 18, 2025 · LEQVIO® is indicated as an adjunct to diet and statin therapy for the treatment of adults with primary hyperlipidemia, including heterozygous familial hypercholesterolemia …