Liquid chromatography–mass spectrometry (LC–MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS).

Mar 17, 2023 · Triple quadrupole mass spectrometers (LC/MS/MS) are established in labs dealing with challenging matrices, as they offer very low detection limits with specificity and selectivity. These factors positively impact the efficiency and cost-effectiveness of laboratory operations.

Nov 8, 2024 · Uncover the inner workings of LCMS and understand how it separates and identifies compounds. Explore the significance of LC/MS in biotech and medical research.

Learn how LC/MS enables the analysis of complex, non-volatile and thermally labile samples including peptides, lipids, alcohols and steroids. Access our extensive collection of mass spectrometry workflows, scientific applications, technical handbooks, webinars and more.

With a focus on the fundamentals of LC/MS, this primer explains the basic principle of operation, theory and technique for the liquid chromatograph (LC), the mass spectrometer (MS), ion source, quadrupole mass analyzer, and detector.

Jul 30, 2024 · LC-MS is an analytical technique that involves physical separation of target compounds (or analytes) followed by their mass-based detection.

Jun 7, 2023 · Liquid chromatography-mass spectrometry (LC-MS) is a powerful analytical technique that combines two selective separation methods. This allows for the isolation, detection, and quantification of analytes of interest, even in highly complex mixtures. LC-MS achieves this by comparing the measured analytes against known reference standards.

Liquid Chromatography–Mass Spectrometry (LC–MS) is a technique that merges the physical separation of HPLC with the remarkable mass analysis capabilities of MS. LC-MS instrument is basically an HPLC unit with a mass spectrometry detector attached to it.

Jul 5, 2024 · Liquid Chromatography Mass Spectrometry (LC-MS) is a powerful analytical technique used in various fields, from pharmaceuticals to environmental science. This blog aims to demystify LC-MS, detailing its principles, applications, and advantages.

Jun 19, 2024 · LCMS is an analytical method that combines liquid chromatography with mass spectrometry. It is used to systematically separate and analyse the compounds present in the sample of interest. LCMS is suitable for separating complicated mixtures and identification of unknown compounds.