The Hippo pathway is a recently identified signaling cascade that plays an evolutionarily conserved role in organ size control by inhibiting cell proliferation, promoting apoptosis, regulating fates of …

Nov 8, 2022 · Here, we review the key components and upstream signals of the Hippo pathway, as well as the critical physiological functions controlled by the Hippo pathway. Additionally, diseases...

Here, we summarize the current understanding of the composition, regulation and function of the Hippo tumor-suppressor pathway, with emphasis on the interplay of Hippo signaling with other signaling …

5 days ago · Expert-reviewed interactive pathway providing a current overview of Hippo Signaling.

Mar 7, 2024 · By integrating diverse mechanical, biochemical, and stress cues, the Hippo pathway orchestrates proliferation, survival, differentiation, and mechanics of cells, which in turn …

Mar 26, 2024 · By integrating diverse mechanical, biochemical, and stress cues, the Hippo pathway orchestrates proliferation, survival, differentiation, and mechanics of cells, which in turn …

Here, we provide an updated review of the Hippo pathway; discuss its roles in development, homeostasis, regeneration, and diseases; and highlight outstanding questions for future investigation …

Here, we review the key components and upstream signals of the Hippo pathway, as well as the critical physiological functions controlled by the Hippo pathway.

3 days ago · In this study, we demonstrate that the WNK-OXSR1 signaling axis is a crucial mediator of tissue regeneration through its regulation of the Hippo signaling pathway. Genetic or …

Mar 15, 2026 · The Hippo signaling pathway has emerged as a key regulator of ferroptosis. By phosphorylating its core effector, YAP1, via a kinase cascade, Hippo signaling inhibits YAP1 …