Jul 1, 2025 · In this issue of the JCI, Zeng et al. demonstrate a provocative and promising therapeutic strategy for TNBC by leveraging the metabolic vulnerabilities presented by …

Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time Katja Wittenzellner, … , Klaus Diepold, Maximilian Reichert Published May 27, 2025 …

You may submit manuscripts for consideration solely by the JCI or select the Dual-Journal Submission option to have your manuscript evaluated by the JCI and JCI Insight. Start your …

Mar 17, 2025 · JCI Insight. 2016;1 (17):e90045. View this article via: JCI Insight CrossRef PubMed Google Scholar Mankia K, et al. EULAR points to consider for conducting clinical …

Open access. Beginning with the January 4, 2022, issue, all content is freely available to the public. The JCI deposits published research articles in PubMed Central, which satisfies the …

Increases in eosinophil numbers are associated with infection and allergic diseases, including asthma, but there is also evidence that eosinophils contribute to homeostatic immune …

Aug 13, 2024 · In this issue of the JCI, Jiang et al. utilized germline mutagenesis to generate a missense variant of GRP75, encoded by the Thinner allele, which resulted in mice with a lean …

Feb 10, 2025 · Idiopathic pulmonary fibrosis (IPF) is an age-related interstitial lung disease, characterized by inadequate alveolar regeneration and ectopic bronchiolization. While some …

Mar 10, 2025 · The copy number of the GJB2 R75W mutation in HeLa cells was determined by real-time qPCR, and 3 copies of the transgene were quantified (Supplemental Figure 1; …

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