What are ACC2 inhibitors and how do they work?
Jun 21, 2024 · Acetyl-CoA carboxylase 2 (ACC2) inhibitors represent a promising frontier in the field of metabolic disease and obesity research. These compounds target ACC2, an enzyme …
ACC2: Great Metabolic Target, Or Total Bust? | Science | AAAS
Apr 8, 2010 · Acetyl CoA-carboxylase 2 (ACC2) has been seen for some years as a target in that area. It produces malonyl CoA, which is a very important intermediate and signaling molecule …
ACC2 Is Expressed at High Levels Human White Adipose and Has …
Feb 3, 2009 · Using RT-PCR, real-time PCR, and immunoprecipitation we report a novel isoform of ACC2 (ACC2.v2) that is expressed at significant levels in human adipose. The protein …
The subcellular localization of acetyl-CoA carboxylase 2 - PMC
Animals, including humans, express two isoforms of acetyl-CoA carboxylase (EC 6.4.1.2), ACC1 (Mr = 265 kDa) and ACC2 (Mr = 280 kDa). The predicted amino acid sequence of ACC2 …
ACC2 is under-expressed in lung adenocarcinoma and predicts …
Our results suggest that ACC2 is a potential diagnostic and prognostic marker that negatively correlated with clinical outcomes in lung adenocarcinoma.
ACC2 - What does ACC2 stand for? The Free Dictionary
Looking for online definition of ACC2 or what ACC2 stands for? ACC2 is listed in the World's most authoritative dictionary of abbreviations and acronyms.
cDNA encoding the 280-kDa acetyl-CoA carboxylase 2 (ACC2) isoform was isolated from human liver using the polymerase chain reaction. Sequencing the cDNA re-vealed an open reading …
ACC2 is under-expressed in lung adenocarcinoma and predicts …
Jan 22, 2022 · In this study, we found that knocking down the expression of ACC2 in lung adenocarcinoma cells can promote proliferation and migration, and bioinformatic analysis and …
Molecular mechanism for the regulation of human ACC2 …
Jan 1, 2010 · Acetyl-CoA carboxylases (ACCs) have been highlighted as therapeutic targets for obesity and diabetes, as they play crucial roles in fatty acid metabolism. ACC activity is …
Acetyl-CoA carboxylases 1 and 2 show distinct expression
Background: Acetyl-CoA carboxylases (ACC) 1 and 2 are central enzymes in lipid metabolism. To further investigate their relevance for the development of obesity and type 2 diabetes, …