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6 days ago · In this issue of the JCI, Maillard et al. identified NUDT5 as a determinant of TP pharmacology. They demonstrated that loss of NUDT5 conferred TP resistance by impairing …
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Volume 135, Issue 14July 1, 2025
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Open access. Beginning with the January 4, 2022, issue, all content is freely available to the public. The JCI deposits published research articles in PubMed Central, which satisfies the …
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Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time Katja Wittenzellner, … , Klaus Diepold, Maximilian Reichert Published May 27, 2025 …
JCI - Deep immunophenotyping reveals circulating activated …
Mar 17, 2025 · JCI Insight. 2016;1 (17):e90045. View this article via: JCI Insight CrossRef PubMed Google Scholar Mankia K, et al. EULAR points to consider for conducting clinical …
JCI - Purifying and profiling lysosomes to expand understanding of ...
Feb 17, 2025 · In this issue of the JCI, Saarela et al. introduce a method called tagless LysoIP that enabled rapid isolation of intact lysosomes from blood and brain cells via …
JCI - A new twist on superantigen-activated autoimmune disease
Jan 16, 2025 · In this issue of the JCI, McCarthy and colleagues used the SKG mouse model of rheumatoid arthritis to characterize the role of Sag activity in inflammatory arthritis by profiling …
JCI - Hidradenitis suppurativa: key insights into treatment success …
Nov 1, 2024 · Hidradenitis suppurativa: key insights into treatment success and failure Kelsey R. van Straalen, 1 Vincent Piguet, 2,3 and Johann E. Gudjonsson 4,5,6