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  1. JCI - Welcome

    6 days ago · In this issue of the JCI, Maillard et al. identified NUDT5 as a determinant of TP pharmacology. They demonstrated that loss of NUDT5 conferred TP resistance by impairing …

  2. JCI - About the Journal of Clinical Investigation

    You may submit manuscripts for consideration solely by the JCI or select the Dual-Journal Submission option to have your manuscript evaluated by the JCI and JCI Insight. Start your …

  3. JCI - Welcome

    Volume 135, Issue 14July 1, 2025

  4. JCI - Author Information Center

    Open access. Beginning with the January 4, 2022, issue, all content is freely available to the public. The JCI deposits published research articles in PubMed Central, which satisfies the …

  5. JCI - Submission instructions - first

    Submit a manuscript directly to the JCI through your account on the JCI’s submission website. Follow the instructions to either register for an account or access your existing account.

  6. JCI Insight - Welcome

    Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time Katja Wittenzellner, … , Klaus Diepold, Maximilian Reichert Published May 27, 2025 …

  7. JCI - Deep immunophenotyping reveals circulating activated …

    Mar 17, 2025 · JCI Insight. 2016;1 (17):e90045. View this article via: JCI Insight CrossRef PubMed Google Scholar Mankia K, et al. EULAR points to consider for conducting clinical …

  8. JCI - Purifying and profiling lysosomes to expand understanding of ...

    Feb 17, 2025 · In this issue of the JCI, Saarela et al. introduce a method called tagless LysoIP that enabled rapid isolation of intact lysosomes from blood and brain cells via …

  9. JCI - A new twist on superantigen-activated autoimmune disease

    Jan 16, 2025 · In this issue of the JCI, McCarthy and colleagues used the SKG mouse model of rheumatoid arthritis to characterize the role of Sag activity in inflammatory arthritis by profiling …

  10. JCI - Hidradenitis suppurativa: key insights into treatment success …

    Nov 1, 2024 · Hidradenitis suppurativa: key insights into treatment success and failure Kelsey R. van Straalen, 1 Vincent Piguet, 2,3 and Johann E. Gudjonsson 4,5,6