ascopubs.org

Molecular profiling and comparative genomic hybridization analysis in human melanoma cell lines and identification of BRAF amplification in a PLX4032 acquired resistance cell line.

Vemurafenib (V) in BRAF V600E metastatic melanoma (mM): Analysis of 507 patients (pts) enrolled in the French temporary authorization for use (ATU). This is an ASCO Meeting Abstract from the 2012 ASCO ...
Kaleido Scope

Cytogenetics Laboratory

The Cytogenetics Laboratory performs chromosome analysis, fluorescence in situ hybridization (FISH), and array comparative genomic hybridization (array CGH) on cells prepared from a wide variety of ...
GEN

Solutions for DNA Copy-Number Analysis

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
ascopubs.org

Genomic Complexity as a Biomarker to De-Escalate Adjuvant Imatinib Treatment in High-Risk Gastrointestinal Stromal Tumor

High-risk patients with genomically simple tumors, defined as ≤ 5 genomic changes, had improved recurrence-free and disease-specific survival compared with patients with complex tumors. Long-term ...
GEN

LOH and DNA Copy Number Changes

Using SNP-CGH to Profile for Amplifications, Duplications, and Deletions The beginnings of personalized medicine have been forged by recent advances in SNP genotyping technologies. It is now possible ...