The mechanistic target of rapamycin (mTOR) pathway coordinates cell growth, metabolism and synaptic plasticity in the central nervous system. Dysregulation of mTOR signalling, often through mutations ...

The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that integrates nutrient, energy and growth-factor signals to coordinate cell growth, proliferation, metabolism and survival.

As the aging population increases, the race to unpack the molecular understanding of aging heats up. The rapamycin (mTOR) complex 1 (mTORC1) is known to be a key component of multiple functions of the ...

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its potential ...

Circulating kidney injury molecule-1 (KIM-1) in association with kidney injury biomarkers and outcomes in metastatic renal cell carcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...