Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
For years, scientists have thought that TGF-Beta, a signaling protein that holds sway over an astonishing array of cellular ...
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This mouse has six legs, but no genitals. Here’s why
The Tgfbr1 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 1. Transmitted by the TGF-β receptor complex, these signals trigger ...
Nature6mon
Inhibition of JNK Enhances TGF-β1-Activated Smad2 Signaling in Mouse Embryonic Lung
Blocking the JNK pathway does not affect TGF-β gene expression and TGF-β binding to its receptors. To determine whether blocking the JNK pathway in mouse embryonic lung explants triggers TGF-β ...
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Kim Sung-jin joins Yale as adjunct professor to enhance cancer research collaboration
Kim Sung-jin joins Yale as adjunct professor to enhance cancer research collaboration CEO Kim Sung-jin advances cancer ...
Medscape4d
Hepatic Fibrosis -- Role of Hepatic Stellate Cell Activation
[6] Initiation refers to early paracrine-mediated changes in gene expression and phenotype ... and via conversion of transforming growth factor (TGF)-beta from the latent to active, profibrogenic ...