Cancer drugs like cisplatin are designed to attack tumor cells, but new research shows these therapies can concentrate inside ...

UCSF scientists found a precise way to turn on cancer-fighting immune cells inside the body. This more potent form of CAR-T has the potential to treat many more cancers.

Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor with the very lipids that carry IL-12 mRNA into tumors, creating a single ...

Dendritic cell sarcomas, encompassing a spectrum of neoplasms derived from accessory immune system cells, represent a rare and diagnostically challenging entity. Among these, follicular dendritic cell ...

Functional precision medicine is helping personalize treatment for patients with brain tumors by testing drugs directly on a patient’s own tumor cells, according to Dr. John Crawford, medical director ...

Researchers have discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new ...

Chimeric antigen receptor (CAR) T-cell therapy has shown efficacy in blood cancers — with six CAR T-cell products now approved by the US Food and Drug Administration (FDA) to treat six hematologic ...

Open-Label, Phase II Trial of Extracellular Regulated Kinase Inhibition Alone and in Combination With Autophagy Inhibition in Patients With Metastatic Pancreatic Cancer Safety and Tolerability of ...

A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor ...

Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study ...