The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which splicing ...
A recent study by TUS researchers reveal that the Cpeb4 protein may have a role in regulating osteoclast differentiation. This, in turn, could lead to the development of new therapeutic drugs for ...
Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...
Computational biologists have uncovered how RNA splicing -- a crucial process for isoform expression and protein diversity -- is regulated across different cell types in the peripheral blood. This ...
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Splicing regulator U2AF1 promotes angiogenesis in cardiac injury
A study published in Engineering shows that a protein called U2 small nuclear RNA auxiliary factor 1 (U2AF1), released by ...
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