Python can then be used to send USB commands in real time. Think of this as doing the same thing the Bus Pirate does for SPI and i2c, except that it’s doing it on the USB protocol itself.

Figure 1 – USB View Tool #2 – PyUSB The cross platform compatibility of Python makes it the perfect programming language to develop USB terminals and application GUI’s. One of the add-on libraries ...

Some of them are connected to native serial ports, and some have USB->RS232 adapters. I am communicating to them via the serial port interface and their /dev/ttyUSB* device nodes.