The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. "Biochemists have been studying ion channels for decades and debating about how they work for almost ...

Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

A new single‑cell method, CIPHER‑seq, measures RNA and proteins together to reveal real‑time cytokine signaling.

Researchers discovered that variations in kinesin motor proteins control selective cargo transport in neurons, enabling ...

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic intent, but real-time activity. By measuring RNA and proteins ...

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, ...

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This ...

Leukemia is adept at dodging the immune system, making it resistant to many of the newest generation of cancer ...

Mechanosensitive recruitment of DLC1 to focal adhesions creates a positive feedback loop that locally amplifies Rho activation in response to tension.

A team led by scientists at King's College London, in collaboration with national and international partners, has discovered how a specific group of immune cells in the gut—Group 3 Innate Lymphoid ...

UCLA researchers have found that specific molecular changes in mice may actually provide protective effects instead of causing harm.