Macromolecular crowding is a central concept in understanding how proteins function in the dense and heterogeneous intracellular environment. In crowded cellular conditions, high concentrations of ...

Proteins are far more than nutrients we track on a food label. Present in every cell of our bodies, they work like nature's ...

Researchers developed a computer simulation that rapidly and accurately predicts how proteins shift their shapes, potentially advancing drug design and protein engineering.

Protein hydrophobicity is a fundamental driver of protein folding dynamics, underpinning the formation of a central hydrophobic core that stabilises the three-dimensional structure amid an aqueous ...

A novel protein cage system can control and visualize orientational changes in aromatic side chains upon ligand binding. By inducing coordinated molecular changes, this approach enables precise ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University observe and model how the enzyme ADAR1 interacts with double-stranded RNA, which may be useful for future cancer ...

For many people, "protein" is the key element of a food order. However, beyond the preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose ...