Mendelian randomization analysis links pork consumption, higher BMI, and T2DM to increased MS risk, while MVPA offers protective benefits. Univariable and multivariable MR analyses confirm causal ...
New data suggested that any level of alcohol consumption raised the risk of dementia. A Mendelian randomization analysis found no evidence that moderate drinking protected against dementia. Findings ...
To try and circumnavigate these issues and strengthen the evidence base, the researchers drew on observational data and genetic methods (Mendelian randomization) from two large biological databanks ...
A Mendelian randomization study reveals PCSK9 inhibitors may reduce low back pain (LBP) risk, while HMGCR and NPC1L1 inhibitors show no significant association, providing genetic evidence for ...
Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as "natural experiments" to reveal ...
The instrument variable assumptions imply that all trains leaving the departure station (genetic variant) and arriving at the destination (outcome) must pass through the exposure station. They can ...
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