Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable ...

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor.

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, ...

A new method combining AFM with deep learning accurately profiles human macrophage mechanophenotypes. Macrophages drive key immune processes including inflammation, tissue repair and tumorigenesis via ...

BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...

New research reveals that aging immune cells can become locked in a self-sustaining inflammatory state, worsening the body’s ...

Angus Chen covers all issues broadly related to cancer including drugs, policy, science, and equity. He joined STAT in 2021 after covering health and science at NPR and NPR affiliate stations. His ...

NETs promote macrophage expression of T-cell chemokines and subsequently facilitate cytotoxic CD8+ T cell infiltration and granzyme B production, which drives kidney fibrosis in obstructive ...

When cancer cells begin to die within tumors, they expose signals on their surface that indicate they are dying. Macrophages then detect these signals and engage in phagocytosis, where they eat the ...