Laser capture microdissection (LCM) is emerging as a premier technology with a point-and-shoot capability designed to rapidly isolate single cells or unique multicellular structures from complex ...

Solid tumors are composed not only of tumor cells but also of stromal nonneoplastic cells. In whole tumor samples, stromal cells retaining their alleles may therefore obscure detection of loss of ...

Understanding genomic variation in the context of cancer is paramount to identifying disease drivers and informing personalized treatment for patients. Tumor heterogeneity presents a challenge in ...

LMD allows researchers to target a specific cell—or even chromosome—and excise it from the cells that surround it on a slide, or in some cases, on a culture dish. 1 Researchers can use some LMD ...

Cutting-edge dual-laser technology delivers power and precision in one device SEATTLE, Nov. 8, 2023 /PRNewswire/ -- Laxco is proud to announce the launch of the Accuva Cellect Laser Capture ...

Spinal cord injury induces profound molecular changes in surrounding tissue. Deciphering these changes with cell type-specific resolution shall facilitate discovery of new molecular targets that ...

This is a preview. Log in through your library . Abstract Iron ranks fourth in the sequence of abundance of the elements in the Earth's crust, but its low bio-availability often limits plant growth.

Retrospective study of the patients with unresectable gastric cancer (UNGC) who underwent a gastrectomy after receiving S-1 or S-1 combination chemotherapy (S-1+α) ...

Microdissection is a method to isolate individual or group of cells from tissue sections. This results in preparation of samples of homogeneous cell types that allows performance of sensitive and ...

Therapeutic implications of phosphoproteomics in molecular cancer diagnostics. Utility of [18F]FDG PET/CT in predicting pathological complete response to neoadjuvant therapy in breast cancer: A ...

Neglecting tissue heterogeneity during the analysis of microRNA (miRNA) levels results in average signals from an unknown mixture of different cell types that are difficult to interpret. Here we ...