Nature

Molecular diagnosis of glycogen storage disease and disorders with overlapping clinical symptoms by massive parallel sequencing

Glycogen storage disease (GSD) is an umbrella term for a group of genetic disorders that involve the abnormal metabolism of glycogen; to date, 23 types of GSD have been identified. The nonspecific ...
ALS News Today

Inflammatory bacterial sugar in gut may drive ALS risk: Study

An inflammatory sugar molecule produced by certain gut bacteria may play a key role in driving ALS, a study found.
Nature

Molecular analysis of the AGL gene: heterogeneity of mutations in patients with glycogen storage disease type III from Germany, Canada, Afghanistan, Iran, and Turkey

Glycogen storage disease type III (GSD III; MIM #232400) is an autosomal recessive inherited disorder caused by deficiency in the glycogen debranching enzyme, a key enzyme in the degradation of ...

The healthy aging brain: How astrocytes store defective glycogen without harming memory

An international research team has uncovered new insights into healthy brain aging. The researchers found that aging leads to the accumulation of defective energy molecules in the brains of aged mice, ...
EurekAlert!

For mice, too much muscle glycogen impairs endurance exercise performance

In 2009, Usain Bolt set the world record in the 100-meter dash, thanks in large part to a carb called glycogen. This molecule is stored in skeletal muscle and later released to fuel short and intense ...