The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...

"This map would reveal the free amount of Dorsal in the nucleus. Once we create it, others would be free to use it so they can advance their understanding of gene regulation." The relationship between ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. The research is published in the journal Nature. The ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

The protein-coding fraction of our genome is like the cast of a Broadway production. Their performance is critical to the success of Biology: The Musical, but a much larger production crew helps ...

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene ...

Livestock breeders could soon have more tools to improve the health and quality of their animals, thanks to a recent study ...

Learn about gene expression studies in progressive supranuclear palsy in Mayo Clinic's Precision Medicine in Neurodegeneration Lab led by Nilufer Ertekin-Taner, M.D., Ph.D.