Total fetal hemoglobin values (milligrams of fetal hemoglobin per 100 ml of blood) were determined in 30 children with acquired aplastic anemia. Seventeen of 18 patients who died (95 per cent) had ...
Dena Goffman, MD, fellow in Maternal-Fetal Medicine, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York Peter S. Bernstein, MD, MPH, FACOG, Associate Professor of Clinical ...
Hemolytic disease of the newborn is a type of anemia that begins during pregnancy. It can cause serious illness in a newborn, but it may be diagnosed during prenatal screening and treated to avoid ...
In early-onset severe hemolytic disease of the fetus and newborn (HDFN), transplacental transfer of maternal antierythrocyte IgG alloantibodies causes fetal anemia that leads to the use of high-risk ...
Subsequently, the surplus accumulation of heme induced cellular stress to the red blood cells, ultimately resulting in anemia. This disruption in intracellular iron distribution due to impaired ...
A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...
A defect in mitochondrial tRNA modification impairs the proper formation of mitochondrial OXPHOS complexes, which results in iron transmigration from mitochondria to cytosol. Excess cytosolic iron ...