Most of the human genome — 98 percent — is made up of DNA but doesn’t actually encode genes ... observed the resulting changes in gene expression. “One example that stood out was a non-coding mutation ...

Much of the "junk" DNA in Drosophila shows signs of either negative or positive selection, according to a study in this week's Nature. An analysis by Peter Andolfatto of the University of California, ...

For example, sometimes our cells make RNA molecules ... some of which came to be used in confusing–and sometimes careless–ways. “Non-coding DNA” came to be a shorthand for DNA that didn ...

For example, the top variant from the screen led to the discovery ... The study serves as a proof of principle of how to take non-coding DNA variants and mechanistically connect them to a trait, such ...

In contrast with previous work, which emphasized changes to protein-coding DNA as driving ... with regulatory evolution in noncoding DNA. The results provide an example for future genome studies ...

Scientists in the U.S. have identified nearly 200 mutations in noncoding DNA that play functional roles ... However, such coding regions account for less than 2% of the human genome and, as ...

The mechanism reveals that damages to non-coding DNA, which are often hidden, accumulate more in slowly proliferating tissues ...

In a new study, stem cell scientists at the Lund University, Sweden, explore the role of non-coding regions ... of our entire DNA—and examined the proteins themselves to find examples of ...

For example, the top variant from the screen ... The study serves as a proof of principle of how to take non-coding DNA variants and mechanistically connect them to a trait, such as chemotherapy ...

When a gene is transcribed from DNA, it often contains many parts that must be removed ... This work revealed that such mutations in non-coding regions can have a significant impact on the levels of ...

Most genes are a sequence of DNA that holds ... of mutations in protein-coding regions is relatively straightforward, but understanding the functions of mutations in noncoding regions presents ...

For example, the top variant from the screen ... The study serves as a proof of principle of how to take non-coding DNA variants and mechanistically connect them to a trait, such as chemotherapy ...