Nature

Comprehensive validation of array comparative genomic hybridization platforms: how much is enough?

Clinical testing using various array comparative genomic hybridization platforms is being incorporated rapidly into cytogenetic testing algorithms. Comprehensive validation of these complex assays ...
Nature

Detection and calibration of microdeletions and microduplications by array-based comparative genomic hybridization and its applicability to clinical genetic testing

Purpose: Genome-wide telomere screening by fluorescence in situ hybridization (FISH) has revealed that ≈ 6% of unexplained mental retardation is due to submicroscopic telomere imbalances. However, the ...
ascopubs.org

Use of microarray-based comparative genomic hybridization analysis to identify prognostic subgroups of ovarian clear cell carcinomas.

Impact of BRCA1 gene alterations on tumor characteristics and clinical outcome in ovarian cancer (OC) patients. Background: Advanced ovarian clear cell carcinomas (OCCCs) are notoriously drug ...
ascopubs.org

Fluorescence in situ hybridization (FISH) and array-comparative genomic hybridization (a-CGH) from percutaneous needle biopsy compared to renal mass histology.

Prognostic factors and validation of prognostic nomograms in patients (pts) treated with three targeted therapies (TTs) for metastatic renal cell carcinoma (mRCC): Results from an Italian survey. This ...