Modifications of the chromatin are crucial for the regulation of nearly all DNA-templated biological processes. Single-cell chromatin modification profiling can be used to assess chromatin ...

Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This tool, a mintbody or modification-specific intracellular antibody, will ...

Catching histones by the tail: A new probe to track histone modifications in living cells Date: September 12, 2016 Source: Tokyo Institute of Technology Summary: Scientists have developed a ...

Laura R. Lee, Diego L. Wengier, Dominique C. Bergmann, Cell-type–specific transcriptome and histone modification dynamics during cellular reprogramming in the Arabidopsis stomatal lineage, Proceedings ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects. They can suppress infection by eliminating viral RNA, such as in ...

Taken together, these results indicate that MIG-17 molecules are secreted from muscle cells after glycosylation by MIG-23, a modification which enables their recruitment to the migrating gonad.

The m6A modification “affects a huge number of messenger RNA in human cells, and yet we did not know its exact function,” said Chuan He, professor in chemistry at UChicago and a recently selected ...

This modification is a process called sialylation. It adds sialic acid-containing N-linked glycans to small RNA molecules to create glycoRNAs. These glycoRNAs can move to the surface of cells, and ...