Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).

In order to better understand how N cadherin functions in neuron migration, Na started screening for other proteins that bind N cadherin. Through two independent screening approaches, the researchers ...

These proteins play important roles in forming tissues that have a specific shape and pattern of cells. To date, we do not fully understand CELSR cadherin structure and function.

Zebrafish midline tissues coordinate their growth during embryonic development using a leader-follower strategy described by ...

Cadherin 17 (CDH17) is a validated biomarker for CRC characterized by its overexpression in tumor tissues (Zheng et al., 2021). CDH17 expression in tissue samples can be reliably detected by ...