Recent research published in Communications Biology marks an advance in structural biology by enhancing understanding of ...

Researchers at the Centre for Genomic Regulation have developed a new technique for identifying allosteric sites in proteins (Nature 2022, DOI: 10.1038/s41586-022-04586-4). While many drugs target the ...

Researchers have identified a hidden allosteric 'on switch' in the ICL2 enzyme of Mycobacterium tuberculosis, offering a new pathway to target drug-resistant strains. Using advanced imaging at the ...

About GT-02287 Gain Therapeutics’ lead drug candidate, GT-02287, is in clinical development for the treatment of Parkinson’s disease (PD) with or without a GBA1 mutation. The orally administered, ...

NEW YORK & GENEVA--(BUSINESS WIRE)--Neurosterix, a biopharmaceutical company dedicated to the development of allosteric modulator therapeutics for underserved neurological disorders, launched today ...

Researchers at the University of Melbourne have identified a hidden allosteric mechanism that activates ICL2, a key enzyme in ...